Thomas amassed 292 yards through the air and David Wilson racked up 88 rushing yards and a TD for the Hokies (3-0).
D.J. Coles had 61 yards on two catches, including a 49-yard touchdown off a short pass, while Danny Coale made seven grabs for 128 yards, including a 4-yard TD, in the Virginia Tech victory.
Ryan Aplin went 16-of-36 for 205 yards but was picked off twice for the Red Wolves (1-2), also adding 53 rushing yards and Arkansas State's lone touchdown.
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