Rasheed Sulaimon netted 15 points and Jabari Parker contributed 11 with 12 rebounds as the Blue Devils (23-6, 12-4 ACC) stayed hot following Saturday's triumph over then-No. 1 Syracuse.
Duke jumped off to an early 20-point lead and was never headed in the Atlantic Coast Conference contest.
The Hokies (9-18, 2-13) were paced by Trevor Thompson with 15 points.
2014: The Year in Music [PHOTOS]