Hancock finished 7-of-9 from the field and Terry Rozier added 16 points for the Cardinals (21-4, 10-2 AAC), who romped to a fourth straight victory.
Wayne Blackshear come off the bench to provide 10 points.
Rutgers (10-16, 4-9) was paced by Kadeem Jack and Myles Mack with 10 points each.
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