The Wildcats remained unbeaten in their three Big East Conference contests and have captured four in a row since their lone loss of the campaign, which came on Dec. 28 against second-ranked Syracuse.
Villanova pulled away in the second half after owning a 38-32 lead at the break. The Wildcats shot 52 percent from the field and connected on 12-of-24 from beyond the arc.
JayVaughn Pnkston added 17 points for Villanova (14-1 overall) and Ryan Arcidiacono had 14.
Seton Hall (10-6, 1-2 Big East) grabbed just two offensive rebounds. The Pirates were led by Brian Oliver with 20 points.
NBC reportedly holds celebs hostage to Jimmy Fallon's show
Aaron Carter is still in love with Hilary Duff