Napier, Ryan Boatright and Niels Giffey combined for eight steals and the Huskies (11-1) recorded eight blocked shots in their second straight win following a Dec. 18 loss to Stanford.
Boatright netted 14 points and Giffey added 13 with four rebounds.
Terrance Samuel came off the bench to provide 12 points with six rebounds and Phillip Nolan swatted aside three shots for UConn.
Tyler Harvey paced the Eagles (5-6) with 19 points.
Dennis Rodman pledges to end trips to North Korea
Interpol investigating stolen passports on missing flight