Nigel Hayes contributed 17 points for the unbeaten Badgers (12-0), who set the mark for most wins starting a season dating back to the basketball program's modern founding in 1946.
Wisconsin used 15 first-half points from Sam Dekker to pull away for the victory.
Frank Kaminsky overcame a foot injury to add 13 points, six rebounds and four assists.
The Colonels (7-4) were paced by Glenn Cosey with 21 points.
Swim Week Miami Beach 2014 [PHOTOS]