Tyler Ennis supplied 17 points, eight assists seven rebounds and four steals for the Orange (8-0), who held the Hoosiers without a field goal during a 12-minute span after the break.
C.J. Fair chipped in 15 points and four rebounds as Syracuse racked up a 47th straight non-conference home win.
Indiana (6-2) was paced by Noah Vonleh with 17 points.
Ray Liotta sues skin care company over use of likeness
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