Four of Daniels' five field goals came from outside the 3-point arc and helped the Rams (23-6, 11-3 A-10) chalk up their seventh win in their last eight starts.
Juvonte Reddic, Treveon Graham and reserve Briante Webber scored 11 apiece for VCU.
Roosevelt Jones led Butler (22-7, 9-5) chipped in 14 points and Khyle Marshall scored 13. Both had six rebounds.
VCU outscored Butler 13-0 in the middle of the second half to blow open a game they had led 45-21 at halftime.