Brown also hauled down six rebounds while Le'Bryan Nash added 16 points as the Cowboys (22-6, 12-4 Big 12) racked up a third straight win.
Phil Forte (14 points) and Marcus Smart (11, six rebounds and four steals) also reached double figures in OSU's victory.
The Longhorns (13-16, 5-11) got a combined 28 points off the bench from Julien Lewis and Jayan Felix, but it wasn't enough to supply Texas with a second consecutive win.
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