Jared Berggren supplied 15 points, eight boards and four blocks as Wisconsin (18-8, 9-4 Big Ten) continued its run of effectiveness against Top 15 teams this season.
The victory marked the fifth time the Badgers have taken out such highly ranked opponents, including previous triumphs over Indiana, Michigan, Illinois and Minnesota.
Sam Dekker (13 points) and Traevon Jackson (10) also reached double figures in the win.
The Buckeyes (18-7, 8-5), meanwhile, fell for the third time in four games despite 18 points and six rebounds from Deshaun Thomas.
Celebrity Families of 2014 [PHOTOS]