C.J. Fair had 19 points and 11 rebounds for the Orange (21-4, 9-3 Big East), who back on the winning track following a Wednesday loss to Connecticut.
Michael Carter-Williams had 14 points and nine rebounds and James Southerland came off the bench to put in 11 points for Syracuse, which forged a tie with Georgetown and Marquette atop the Big East standings.
The Pirates (13-13, 2-11) got 21 points from Fuquan Edwin.
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