The Panthers (19-5, 7-4 Big East) stayed hot with their sixth win in seven games with the help of Steven Adams, who provided added eight points and a career-high 15 rebounds.
Fuquan Edwin drained a trio of 3-pointers en route to 23 points for the Pirates (13-10, 2-8).
The loss was the eighth in nine contests for Seton Hall.
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