Jake Odum and Devonte Brown supplied 10 points apiece as Indiana State (14-7, 7-3 MVC) used a tough defense to hold the Shockers to just 27.1 percent shooting from the field.
Cleanthony Early provided 15 points and 11 rebounds, but it wasn't enough for Wichita State (19-3, 8-2), which saw its 19-game home winning streak snapped.
Demetric Williams scored 14 points in the loss.
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