Holloway also supplied eight rebounds and four steals while Jarvis Summers added 12 points for Ole Miss (13-2, 2-0 SEC).
Marshall Henderson also reached double figures with 11 points for the Rebels.
The Tigers (12-3, 1-1), meanwhile, fell for the second time in four games.
Jabari Brown supplied 13 points with eight rebounds and Keion Bell chipped in with 11 and seven in the loss.
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