Grant scored 19 points on 7-of-10 shooting from the field and Scott Martin drained four 3-pointers en route to 12 points for the Fighting Irish (14-1, 2-0 Big East), who grabbed control of the game with a 10-0 run midway through the second half.
Jack Cooley (11 points, eight rebounds), Eric Atkins (10, six assists) and Pat Connaughton (10, six boards) also reached double figures for Notre Dame, which reeled off its 12th straight victory.
Sean Kilpatrick put in 15 points for the Bearcats (13-3, 1-2), who dropped their third in four contests.
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