Will Yeguete added 14 points and nine rebounds for the Gators (10-2), who shot a sizzling 60 percent from the field en route to their second straight win.
Florida also got 13 points, three rebounds and three steals from Mike Rosario.
Yale (5-11) was paced by Justin Sears with 15 points and four steals.
Javier Duren (14 points) and Armani Cotton (12) also reached double figures for the Bulldogs.
2014: The Year in Music [PHOTOS]