Hollins also had six assists while Rodney Williams contributed 15 points and six rebounds for the Golden Gophers (13-1, 1-0 Big Ten).
Trevor Mbakwe provided a double-double of 11 points and 12 rebounds as Minnesota reeled off its ninth consecutive victory.
The Spartans (11-3, 0-1), meanwhile, saw their six-game winning streak broken despite 15 points, six steals and five assists from Keith Appling.
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