Zeller played only 22 minutes, but hit 6-of-9 from the field and was 12-of-13 from the line in scoring 24 points. Notre Dame went 26-of-27 from the charity stripe while improving to 11-1.
Indiana has put together two one-sided triumphs since suffering an overtime loss to Butler last Saturday that knocked the Hoosiers out of the No. 1 spot in the national rankings.
The Hoosiers held Florida Atlantic scoreless for a 5-minute stretch in the first half and took a 55-25 lead at halftime.
Christian Watford pitched in 17 points for the Hoosiers and Victor Oladipo had 16 while making 6-of-8 from the field.
Florida Atlantic (5-7) managed just 19 field goals for the game and was led by 25 points by Greg Gantt. It was the Owls' fourth straight loss.