Ben McLemore (14 points, seven boards), Travis Releford and Naadir Tharpe (11 points each) also reached double figures as the Jayhawks (9-1) cruised to their eighth straight win.
Kansas used an 18-0 run in the first half to put the game away.
The Spiders (9-3) were paced by Derrick Williams with 14 points with five rebounds.
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