Ryan Harrow added 12 points for the Wildcats (7-3), who won their third straight following consecutive losses to Baylor and Notre Dame.
Alex Poythress (11 points) and Archie Goodwin (10) also reached double figures in scoring for Kentucky, which led 43-29 at halftime.
Martin Smith pumped in 18 points and Stephen Hurt added 12 and 11 rebounds for the Bisons (4-5).
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