Dranginis hit 12-of-16 shots from the field while the Bulldogs were handing their Division 3 opponent its first loss of the season.
Gonzaga climbed to 7-0 with Dranginis hitting four 3-pointers to go with seven assists and six rebounds. Przemek Karnowski added 16 points while making 8-of-10 field goal attempts.
The Warriors (9-1) were led by P.J. Bolte with 10 points. Lewis & Clark turned the ball over 21 times.