The victory put the Wolfpack into the championship game of the Puerto Rico Tip-Off Tournament. North Carolina State will meet Oklahoma State in the finals on Sunday.
North Carolina State raced to a 16-point halftime lead and had no trouble holding on to post its third victory in as many games.
Richard Howell added 19 points and Scott Wood had 15 for the Wolfpack, who shot 56 percent from the field.
The Minutemen (2-1) were led by Jesse Morgan with 15 points. Massachusetts reached the semifinals with a victory over Providence on Thursday.
'How to Train Your Dragon 2' releases 5-minute clip
Lytro unveils camera that can focus a photo after shooting it