Murphy made all 10 of his attempts from the field and hit both of his shots from the foul line as part of Florida's overall outstanding effort. The Gators went 61 percent from the field and converted 6-of-12 from 3-point range.
The Gators have won their opening two games of the season. Wisconsin dropped to 1-1.
Florida did not score during the final 3 minutes of the first half, but then ran off the first seven points of the second period to take a 50-31 lead.
Murphy finished with 24 points and eight rebounds. Mike Rosario added 15 points and Kenny Boynton had 10.
Florida overcame its 20 turnovers by outrebounding Wisconsin 39-21.
Jared Berggren and Sam Dekker led the Badgers with 11 points each.