Boynton also dished off four assists for the seventh-seeded Gators (25-10), who now advance to the Sweet 16 to take on No. 3 seed Marquette in the West Region semifinals.
Erving Walker contributed 15 points, while Bradley Beal supplied 14 and nine boards in Florida's victory.
The Spartans (26-10) were led by Marcos Tamares' 12 points.
Notable deaths of 2014 [PHOTOS]