The Wildcats (6-0) won for the 36th straight time at home thanks, in part, to 14 points and eight assists from Marquis Teague. Anthony Davis added 13 points, 12 rebounds and five blocks.
Michael Kidd-Gilchrist finished chipped in 11 points for Kentucky.
The Pilots (2-4) lost their fourth straight despite a game-high 20 points from Nemanja Mitrovic.
Celebrity Families of 2014 [PHOTOS]