Blackshear, selected as a member of the McDonald's High School All-American team last season, suffered a torn labrum in his right shoulder during practice. He will require surgery.
As a high school senior in the Chicago area, Blackshear averaged 32.6 points, 14.6 rebounds and 5.6 assists per game.
Louisville is ranked eighth in the pre-season poll of college coaches.
Notable deaths of 2014 [PHOTOS]