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Oct. 27, 2016 / 6:04 PM

Buffalo Bills RB LeSean McCoy sits with sore hamstring

Buffalo Bills running back LeSean McCoy (25) looks for running room on a carry in the fourth quarter against the New England Patriots at Gillette Stadium in Foxborough, Massachusetts on October 2, 2016. The Bills defeated the Patriots 16-0. Photo by Matthew Healey/ UPI

Buffalo Bills running back LeSean McCoy (25) looks for running room on a carry in the fourth quarter against the New England Patriots at Gillette Stadium in Foxborough, Massachusetts on October 2, 2016. The Bills defeated the Patriots 16-0. Photo by Matthew Healey/ UPI | License Photo

Buffalo Bills running back LeSean McCoy missed his second straight day of practice on Thursday, raising concerns about his availability for Sunday's home game against the New England Patriots.

McCoy, who is nursing an ailing hamstring, was limited in last Friday's practice and didn't fare well two days later in a 28-25 loss to the Miami Dolphins. The 28-year-old rushed eight times for 11 yards before exiting the contest in the third quarter.

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McCoy performed considerably better in the first meeting with the Patriots, a 16-0 win for Buffalo on Oct. 2. He rushed for 70 yards and reeled in a season-best six catches for 38 yards and a touchdown.

McCoy has rushed 112 times for 598 yards with six touchdowns this season. He also has 20 catches for 97 yards and a score.

Wide receiver Marquise Goodwin, safety Aaron Williams, left tackle Corey Glenn and linebacker Zach Brown also missed their second practice of the week on Thursday.

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