The Goats, who will be the designated road team for Sunday's affair, have not claimed a win at the StubHub Center since their season-opening defeat of the Chicago Fire on March 9.
Chivas has dropped its last three home games by a combined score of 9-1, most recently suffering a humiliating 3-0 defeat to the Philadelphia Union.
But Wilmer Cabrera's men will turn the page on disappointing home spell with the hopes of bouncing back against a bitter rival.
"Right now what we need, obviously, is to forget about the last game against Philadelphia because different things happened that were not normal for any kind of soccer game," Cabrera told reporters following the team's training session on Tuesday. "Now we just have to think that we have another opportunity and we have to find the way to come back."
Like the majority of the league, the Galaxy have gotten the better of Chivas at large, but the Goats will be hoping to toss its inferior head-to-head record aside and claim a positive result.
"You don't have to prepare too much for this game in terms of what you do on the field because they're going to be ready," Cabrera said. "They want to play this game. This is the game that you want to play against the rival, against the other team you share home with, you share the field with and it's a beautiful opportunity that no matter what position you are in the standings, you are going to play like it's a special game."
Los Angeles enters the clash in much better form, riding a three-game unbeaten streak that has seen the club take seven points during that stretch.
Landon Donovan has been firing on all cylinders following his snub from the United States national team's World Cup team. The 32-year-old bagged a brace in the Galaxy's 4-1 throttling of the Philadelphia Union before netting the equalizer in the club's 1-1 draw with the Chicago Fire on Sunday, a match marked by extreme heat and humidity.
"Not his best day but he got a goal and he hung in there for 90 minutes so that was good," Galaxy head coach Bruce Arena said of Donovan's performance. "It was a lousy game today. There's no other way to put it. I think Chicago played a little bit better than us, but the conditions were difficult for both teams and it made for a not-good game."
Los Angeles has played just 11 games in league action this term, the second- fewest in MLS thus far. That has kept the club out of the playoff picture as the Galaxy enter the weekend in sixth place in the Western Conference on 16 points.
Chivas, tied for the league-low with just two wins, sits at the foot of the West table on 10 points.