Julio Teheran (0-1) walked Jean Segura to start off the bottom of the fourth and Ryan Braun's line-drive single to left provided the Brewers with men at first and third and no outs. Braun then stole second before Ramirez's liner down the left-field line brought both runners around to make it a 2-0 game.
Jonathan Lucroy, Scooter Gennett and Ramirez all went 2-for-3 for the Brewers. Yovani Gallardo (1-0) surrendered four hits and two walks with four strikeouts across six scoreless innings, while Francisco Rodriguez struck out two batters in the final frame to earn the save.
Andrelton Simmons had two of the Braves' five hits in the loss. Teheran conceded both runs on seven hits with one walk and two strikeouts in six innings of work.
The first overturned play under the new replay challenge system occurred in the bottom of the sixth. Braun was initially called safe on a single after he grounded over to third. Chris Johnson's throw from third to first appeared to beat Braun, but first base umpire Greg Gibson deemed the runner safe.
Atlanta manager Fredi Gonzalez quickly came out of the dugout to challenge the call. The replay showed that the throw beat Braun's foot to the bag and the replay headquarters in New York overturned the call on the field.