The Bears closed the contest on a 20-8 run to become the second straight Atlantic Sun team to provide an NCAA surprise. Last year, it was Florida Gulf Coast that knocked off second-seeded Georgetown on the way to the Sweet 16.
Duke, which finished the season ranked eighth in the country, lost its NCAA Tournament opener for the second time in three years.
Notable deaths of 2014 [PHOTOS]
LeBron James reveals his new Nike shoes