Avery Bradley paced Boston with 23 points, while Brandon Bass tallied 18 and Jared Sullinger added 14 off the bench to help the Celtics snap a five-game losing streak.
The Heat played without four-time MVP LeBron James because of back spasms and were led by Dwyane Wade's 17 points.
Chris Andersen scored 16 points with eight rebounds off the bench and Udonis Haslem and Ray Allen contributed 14 points each for Miami, which had a two- game winning streak snapped.
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Rajon Rondo nearly recorded a triple-double with nine points, 10 rebounds and 15 assists to lead the Boston Celtics to a 101-96 victory over the Miami Heat on Wednesday.