Seratelli, pinch-running for Omar Quintanilla, stole second and moved to third on a throwing error by catcher Bryan Holaday on the play. Brown then followed with his game-winning hit.
Eric Campbell ended 2-for-4 with a homer for the Mets.
Miguel Cabrera and Tyler Collins each homered for the Tigers. Both players have three homers this spring.
Detroit's Kyle Lobstein got the start and yielded one run on one hit in 2 2/3 innings of work. The lefty struck out two and walked two.