Dwight Powell accounted for 15 points for the sixth-seeded Cardinal (21-11), followed by Josh Huestis and Anthony Brown with 12 and 11 points, respectively, not to mention a combined 13 rebounds from the pair.
The third-seeded Sun Devils (21-11) were led by Jonathan Gilling with 13 points, followed by Bo Barnes and Shaquielle McKissic with 12 points apiece and Jahii Carson 10 in the setback.
Stanford scored the first points of the contest and never looked back, moving out to a 30-27 advantage at the break after holding ASU to a mere 9-of-25 shooting from the field.
In the second half the Cardinal erupted for a staggering 70.8 percent accuracy from the floor, including 5-of-7 beyond the arc, as they cruised to the comfortable victory.
Arizona State, which pulled down just two offensive rebounds on the night, had almost as many points off the bench (25) as it did from the starters (33).
The Cardinal now move to the semifinals on Friday night and will face UCLA which defeated Oregon by a lopsided 82-63 score earlier on Thursday.