Kevin Martin scored 26 and J.J. Barea netted 19 points for the Timberwolves, who have won five of their last seven. Nikola Pekovic added 14 points and eight boards and Ricky Rubio tallied 11 points and 10 assists.
After trailing by as many as 11 in the first half Minnesota used a 20-8 run three minutes into the second half and led 81-76 with 2:47 left in the third. The Bucks pulled back within two, 86-84, heading into the final frame.
The T'Wolves took complete control as they opened the fourth quarter with a 19-4 tear. Minnesota staked themselves a 17-point lead, 105-88, with 5:07 left on the clock. Milwaukee trailed by double-digits through the final seven minutes of play.
"We had some bad shot selection in the fourth quarter, and on the road those are as good as a turnover," Milwaukee head coach Larry Drew said.
The Bucks started the game with the hot hand and knocked down 15-of-21 from the floor in the first quarter. The Bucks led 33-28 heading into the second quarter.
"We were too soft. They made shots, but we let them go wherever they wanted to go," Minnesota head coach Rick Adelman said of the slow start.
The T'Wolves knotted the game at 40 apiece with 7:14 left in the first half. There were two more ties and four lead changes over the next three-plus minutes before the Bucks ended the half with a 12-6 run. Minnesota trailed 61-55 at halftime.