Nordqvist had four birdies, an eagle and a bogey for a third-round score of 5-under-par 67 that put her at 11-under 205 for the tournament.
World No. 1-ranked Inbee Park, the tournament defending champion, also shot 67 Saturday and pulled into a tie for second with Michelle Wie, had a bogey-free 69 in the third round. They are at 7-under.
Nordqvist opened the third round with a one-stroke lead and, after a birdie at the second hole and a bogey at No. 5, was even on the day through nine holes.
She started to pull away with an eagle at the par-5 10th and added birdies at Nos. 12 and 15. A birdie at 18 pushed the advantage to four strokes.
Nordqvist is looking for her third LPGA title. The first two came in her rookie season of 2009.