George went 5-of-7 from 3-point range en route to 32 points and West went 11-of-16 from the field, finishing with 30 points for Eastern Conference-leading Indiana.
Lance Stephenson supplied 24 points, nine rebounds and eight assists.
Milwaukee's Brandon Knight scored 30 and handed out eight assists as the Bucks lost for the sixth time in seven games.
Notable deaths of 2014 [PHOTOS]
Julius Randle breaks leg during NBA debut