Spain's Ferrer, ranked fifth in the word, continued his dominance in Buenos Aires with a 6-4, 6-3 victory over the second-seeded Fognini.
The win enabled Ferrer to break a five-match losing streak in finals stretching back to his win over Stanislas Wawrinka in last year's Copa Claro championship tilt.
The Spanish star has pulled off three-peats twice previously -- at Acapulco (2010-12) and Auckland (2011-13).
Fognini, meanwhile, fell to 0-7 all-time against Ferrer.
Notable deaths of 2014 [PHOTOS]