Mirza Teletovic, Andray Blatche and Deron Williams each provided 13 points for Brooklyn, which downed the Bobcats for a fifth straight meeting.
Kevin Garnett added 10 points as the Nets logged a fourth consecutive home victory.
Charlotte was paced by 16 points from Kemba Walker.
Al Jefferson added 12 points and 10 rebounds.
Rosie O'Donnell unveils nearly 50-pound weight loss
Members of Congress to keep receiving porn magazine