West totaled 22 points with 10 rebounds and George provided 18 and seven for the Pacers, who broke a 12-game losing streak at Philips Arena with their first win in Atlanta since Dec. 22, 2006.
Lance Stephenson netted 10 points before leaving with a sore lower back following a nasty fall.
Mike Scott came off the bench to lead Atlanta with 15 points.
All-Star forward Paul Millsap was limited to seven points to go with 12 rebounds.
Celebrity Families of 2014 [PHOTOS]