Durant played just 31 minutes and hit 10-of-12 from the field. He had scored at least 30 points in each of his previous 12 games, including a career-best 54 against Golden State on Jan. 17.
The Thunder built a 63-35 halftime lead en route to their 10th straight victory. They have 38 victories for the season, most in the NBA, and were coming off a 17-point win in Miami on Wednesday.
Oklahoma City will end a three-game road trip in Washington on Saturday.
Serge Ibaka added 25 points and nine rebounds for Oklahoma City and both Thabo Sefolosha and Reggie Jackson had 14 points. The Thunder made 49-of-77 shots from the field.
Brooklyn has dropped two straight after winning 10 of 11. The Nets were led by Shaun Livingston with 16 points.