Kemba Walker struck for 25 points, seven rebounds and five assists as the Bobcats snapped a three-game skid.
Gerald Henderson contributed 17 points.
The Knicks had their five-game winning streak ended despite 20 points from Carmelo Anthony.
Amar'e Stoudemire put in 17 for New York.
2014: The Year in Fashion [PHOTOS]
UPI Sports Results for September 19, 2014