Dalton's TD run early in the fourth quarter provided the difference for the AFC North champion Bengals (11-5), who completed a perfect 8-0 home record for the second time in franchise history.
Dalton overcome four interceptions, completing 21-of-36 passes with a pair of TDs.
Cincinnati wrapped up the win on Dre Kirkpatrick's 21-yard pick-off return for a score with 4:07 remaining.
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