Plumlee scored 22 points with 13 rebounds, Dragic had 21 points and Bledsoe finished with 20 as Phoenix pulled away in the second half for an eighth win in 11 games.
Marcus Morris came off the bench to pop in 18 points.
Thaddeus Young notched a double-double of 30 points and 10 rebounds for the struggling 76ers, who lost a 13th straight on the road and fell to 1-9 in their last 10 games overall.
Michael Carter-Williams provided 27 points, six assists, six rebounds and four steals.
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