George had 24 points and Stephenson had nine rebounds and seven assists to go with his 23 points as Eastern Conference-leading Indiana shot 53.5 percent in downing Brooklyn for the second time within a week.
The Pacers, who also beat the Nets Monday in New York, notched a fourth straight victory overall.
George Hill put in 21 points for Indiana.
Paul Pierce led Brooklyn with 18 points. Mirza Teletovic added 17 as the Nets fell for the fifth time in their last six games overall.