The broadcaster said the NFL's leading rusher, who was hurt during the snow-filled first half of Sunday's game at Baltimore, was transported from the stadium to a local hospital for magnetic resonance imaging tests on the ankle.
Peterson was hurt while being tackled along the sidelines in deep snow at M&T Bank Stadium. He was seen walking under his own power along the sidelines before leaving for the trainer's room.
Peterson was listed as questionable for the start due to a strained groin.
He had racked up 1,206 yards on 261 carries with 10 touchdowns entering Sunday's games.