Durant's fourth career triple-double helped the Thunder explode for 35 points in the fourth quarter, wiping out an 11-point deficit en route to a seventh straight win.
The Timberwolves were led by Kevin Martin's 24 points.
Nikola Pekovic (22, 10 rebounds) and Kevin Love (16, 12) each had a double-double for Minnesota, which lost for the sixth time in eight games.
Notable deaths of 2014 [PHOTOS]
Michael Sam cut from the Dallas Cowboys