Penner came up with a power-play goal in the first period and provided the go-ahead score in the second -- the first of three consecutive Anaheim goals that wrapped up the win.
Hiller made 42 saves as the Ducks won a second straight.
Corey Perry and Sami Vatanen each scored for Anaheim.
The Coyotes, meanwhile, dropped a third in four games despite a goal and an assist from Shane Doan.
Celebrity Couples of 2014 [PHOTOS]