The Clippers won their third in a row and remained unbeaten in their four home games. Oklahoma City had a four-game winning streak halted.
Los Angeles had a 12-point lead with 6:30 to play in the game, but Oklahoma City cut its deficit to four on a 3-pointer from Reggie Jackson with 3:29 remaining.
Crawford then hit a jumper, after which Russell Westbrook missed two foul shots for the Thunder. Crawford followed with a layup to increase the lead to eight.
Oklahoma City's Kevin Durant made 15-of-17 free throws and finished with 33 points to go with 10 assists.