It was the Pelicans first win over the Lakers in their last 12 meetings. New Orleans had not downed Los Angeles since March, 2010.
The Pelicans scored 12 straight points in the first period with Davis accounting for seven of them. New Orleans pulled away in the fourth quarter to win back-to-back games for the first time this season.
Davis made 12-of-18 from the field and 8-of-11 from the foul line. He also had 12 rebounds and equaled his career high with six blocks.
Los Angeles was led by 16 points from Chris Kaman. The Lakers were unable to build on their one-point win in Houston on Thursday.