The Cavaliers jumped in front by 14 after one period only to see the 76ers dominate the middle two quarters. Philadelphia took a 16-point lead into the final period and easily held on to end a two-game skid.
Turner added 10 rebounds while Tony Wroten delivered a career-best 18 points off the bench. Thaddeus Young added 16 points for the 76ers.
Tristan Thompson had 13 points and 16 rebounds for Cleveland, which has lost back-to-back games.
Cleveland center Andrew Bynum received a less-than-warm welcome from his former home crowd while scoring four points in 18 minutes. He was booed by the Philadelphia fans after sitting out all of last season with knee problems while with the 76ers.